For researchers seeking tlb-150 benzoate for sale uk, the choice between liquid and capsule formulations is not always straightforward. The market offers multiple formats, each with distinct handling requirements and dosing considerations. This guide compares RAD-150 (TLB-150 Benzoate) liquid and capsule options, examines the compound’s extended half-life profile, and explains why third-party purity verification matters when sourcing research compounds across the UK.
Understanding RAD-150: The Benzoate Ester Advantage
RAD-150, also known as TLB-150 Benzoate (CAS 1208070-53-4), is a nonsteroidal selective androgen receptor modulator (SARM) classified as the benzoate ester derivative of RAD-140 (Testolone) . The compound belongs to the aryl propionamide class of SARMs and features a benzoate ester moiety that modifies its lipophilicity and metabolic stability .
Extended Half-Life
The defining characteristic of RAD-150 is its extended elimination half-life. While the non-esterified parent compound RAD-140 exhibits a half-life of approximately 16–20 hours, RAD-150 demonstrates an estimated 48-hour half-life . This approximately 2.5- to 3-fold extension is attributed to benzoate esterification, which increases lipophilicity (LogP = 5.4) and alters tissue distribution kinetics .
| Parameter | RAD-150 | RAD-140 |
|---|---|---|
| Elimination half-life | ~48 hours | 16–20 hours |
| LogP | 5.4 | Not specified |
| AR IC50 | 130 nM | Ki: 7 nM |
Androgen Receptor Binding
RAD-150 demonstrates androgen receptor modulation with an IC50 of 130 nM (0.13 μM) in competitive binding assays . It is important to note that IC50 values and Ki values represent distinct measures of receptor interaction and should not be directly compared without assay-specific conversion factors. RAD-150 is intended for in vitro and preclinical research applications only.
Product Specifications
When sourcing hplc tested rad-150 uk, look for these key parameters:
- CAS Number: 1208070-53-4
- Molecular Formula: C₂₇H₂₀ClN₅O₃
- Molecular Weight: 497.93 g/mol
- Purity Standard: ≥98% HPLC-verified, with some reference materials achieving 98.3% purity
Liquid vs Capsules: Format Comparison
Capsule Formulations
Capsules are available in pre-measured dosages from UK suppliers, offering convenience and consistency for standardised research protocols.
| Supplier | Format | Dosage | Price |
|---|---|---|---|
| Shapeshifter Nutrition | Capsules | 5mg x 90 | £49.99 |
| BioLabShop | Capsules | 10mg x 60 | £41.99 |
Advantages of capsules:
- Pre-measured dosing eliminates handling errors
- Ready for immediate use with no preparation
- Batch-verified for consistency
Considerations:
- Limited flexibility for dose adjustments
- Contains excipients (fillers/binders)
Liquid Formulations
Liquid RAD-150 is typically offered as a research solution, providing greater flexibility for varied research protocols. For researchers in cities like London or Manchester seeking rad-150 10mg capsules London or liquid alternatives, the choice depends on specific protocol requirements.
Advantages of liquid:
- Adjustable dosing volumes
- Typically fewer excipients
- May be preferred for certain experimental designs
Considerations:
- Requires accurate measurement equipment
- Potential for handling errors
Storage and Handling Considerations
Proper storage is essential for maintaining compound integrity. RAD-150 demonstrates specific storage requirements that differ from non-esterified SARMs:
As an ester compound, RAD-150 is susceptible to base-catalyzed hydrolysis under certain conditions. Forced degradation studies indicate that the primary degradation pathway is expected to be hydrolytic cleavage of the ester bond, yielding RAD-140 and benzoic acid.
Why Buy RAD-150 From SARMs Store?
When sourcing tlb-150 benzoate for sale uk or order tlb-150 benzoate Manchester, trust signals matter. We ensure:
- Quality control: Batch-verified formulations with documented purity
- UK-based fulfilment: Fast domestic delivery reducing customs delays
- Research-grade integrity: Products labelled for laboratory and educational research only
- Full documentation: Supporting laboratory record-keeping requirements
📞 Need Help Choosing Your RAD-150 Format?
Whether you require capsules or liquid, our team can assist with questions about purity verification and storage protocols.
Common Buyer Scenarios
The Protocol-Specific Researcher: You require pre-measured doses for a standardized protocol. Capsule formats (5 mg or 10mg) offer convenience and consistency.
The Flexible Researcher: You need to adjust dosing volumes. Liquid formulations provide greater control over dosage.
The Quality-Focused Laboratory: You require HPLC-verified purity. Look for batch-specific COAs with ≥98% purity documentation .
The Comparative Buyer: You are evaluating RAD-150 against RAD-140. The extended half-life may suit protocols requiring less frequent dosing in chronic administration studies.
Research Applications and Considerations
RAD-150 is supplied strictly for laboratory and educational research purposes. Applications include:
- Androgen receptor binding studies: Evaluating receptor modulation and tissue selectivity
- Pharmacokinetic research: Investigating esterification effects on half-life and tissue distribution
- Muscle and bone receptor studies: Evaluating anabolic pathways under controlled conditions
Important Notes
- RAD-150 is not a medicine, dietary supplement, or therapeutic product
- Generic substitution between RAD-150 and RAD-140 is scientifically invalid due to fundamental differences in chemical structure and pharmacokinetic profile
- The benzoate ester influences compound stability; specific storage requirements differ from non-esterified SARMs
Conclusion
When seeking tlb-150 benzoate for sale uk for research applications, the choice between capsules and liquid should be informed by your specific protocol requirements, handling preferences, and storage capabilities. Capsules offer convenience and pre-measured consistency, while liquid provides flexibility for varied dosing protocols. Always prioritize suppliers who can provide batch-specific purity verification (≥98% HPLC) and clear storage instructions. The extended half-life of RAD-150 (approximately 48 hours) may be suitable for research protocols requiring less frequent dosing in chronic administration studies .